Score the counterfactual class-conditional VAE single-sample discriminator
Source:R/singlesample-cvae-scorer.R
score_cvae.RdScores each row of X independently with the frozen model from
fit_cvae, in PURE R (no python). Each query is mapped to the
per-sample robust CLR over the frozen feature universe (absent universe features
carry the neutral rCLR value 0), then scored by the counterfactual evidence
log-likelihood ratio \(s(x) = \mathrm{ELBO}(x,\mathrm{case}) -
\mathrm{ELBO}(x,\mathrm{control})\) using the latent MEAN \(z = \mu\)
(DETERMINISTIC – no sampling, no RNG). Larger = more case-like.
Queries with fewer than model$hp$min_features universe features present (a
column-overlap floor), or empty positive support over the frozen universe on the
(pre-rCLR) aligned abundances (!any(X_use[i, ] > 0)), return the neutral
score 0. A FLAT all-equal-positive composition maps to the rCLR origin but
is a VALID specimen and is scored normally. The score of a row depends only on that
row and the frozen model and is exactly invariant to per-specimen positive scaling.
Arguments
- model
A
cvae_modelobject fromfit_cvae.- X
Numeric matrix (samples \(\times\) features) of non-negative abundances with named feature columns.
- meta
Optional per-sample metadata. Accepted for interface uniformity and ignored by this method.
Examples
if (FALSE) { # \dontrun{
model <- fit_cvae(X, y)
score_cvae(model, X[1, , drop = FALSE])
} # }