Score baseline robust CLR for provenance-aware benchmark comparisons

Score baseline robust CLR for provenance-aware benchmark comparisons

Usage

score_baseline_rclr(
  expr,
  meta,
  panel,
  cohort_col = "cohort",
  block_col = "provenance_block",
  pseudocount = NULL
)

Arguments

expr

Numeric matrix, samples x features.

meta

Data frame aligned to `expr`.

panel

Character vector of panel features.

cohort_col

Column in `meta` identifying cohorts.

block_col

Column in `meta` identifying provenance blocks.

pseudocount

Optional additive pseudocount before log transform.

Value

Numeric score vector.