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Fit a RIN-weighted frozen reference profile on training samples only.

Source: R/singlesample-anchor-denoising.R
fit_rin_weighted_reference.Rd

Fit a RIN-weighted frozen reference profile on training samples only.

Usage

fit_rin_weighted_reference(
  expr,
  meta,
  rin_col = NULL,
  cohort_col = "cohort",
  pseudocount = NULL
)

Arguments

expr

Numeric matrix, samples x features.

meta

Data frame aligned to `expr`.

rin_col

Optional RNA-integrity-number column.

cohort_col

Column identifying training cohorts.

pseudocount

Optional additive pseudocount before log transform.