Fit the hemolysis plus kit-stable dual-anchor denominator.

Fit the hemolysis plus kit-stable dual-anchor denominator.

Usage

fit_hemolysis_kit_dual_anchor(
  expr,
  meta,
  kit_col = NULL,
  cohort_col = "cohort",
  anchor_fit = NULL,
  pseudocount = NULL,
  ...
)

Arguments

expr

Numeric matrix, samples x features.

meta

Data frame aligned to `expr`.

kit_col

Optional kit column.

cohort_col

Column identifying training cohorts.

anchor_fit

Optional precomputed `kit_stable_anchor_fit`.

pseudocount

Optional additive pseudocount before log transform.

...

Additional arguments passed to `fit_kit_stable_anchors()`.