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Use combat to fight batch effect.

Usage

OmicSelector_combat(
  danex,
  metadane = metadane,
  model = c("~ Batch", "~ Batch + Class")
)

Arguments

danex

Matrix with miRNA normalized expression values (e.g. TPM, deltaCt) with miRNAs in columns and cases in rows.

metadane

Metadata with `Class` and `Batch` variable.

model

Model of correction (application of covariates).

Value

Batch-corrected dataset.